Antihyperlipidaemic Activities of Agriophyllum squarrosum (L.) Moq. in vivo

Sun Zhaorigetu, Wu Yuling, Damdindorj Mungunnaran, Ochir Sarangowa, Borjihan Gereltu


Agriophyllum squarrosum (L) Moq. is medicine herb used as a traditional Mongolian drug. Its pharmacological efficacy studies are rarely reported. In the present study, we tested and confirmed the antihyperlipidaemic activity of A. squarrosum and its extracts in rats for the first time. The results of the antihyperlipidaemic experiment in vivo showed that A. squarrosum and its extracts had significant lipid-lowering activities. The significances of A. squarrosum and its extracts on decreasing blood levels of total cholesterol, triglyceride, and low density lipoprotein cholesterol were equal to that of simvastatin, which is a drug for the treatment of hyperlipidaemic.


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ISSN 1684 (print edition), ISSN 2225-4994 (online edition)